ECETOC members, academics, regulators and scientists from NGOs are still in time to join our recently launched Task Forces:Smart studies: Examine how in vivo studies could provide more informati...
The Centre for chemical safety assessment (ECETOC) convened an online workshop on 20 – 21 January 2022 to bring together experts from industry, regulatory and academic arenas to discuss how best to...
This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
Background
There are currently many intense global activities on adverse outcome pathways (AOP). Much of this activity is focused on endocrine disruption (ED). There is a risk that AOPs will be use...
Background
In the EU the fate of chemicals in wastewater treatment is currently simulated with SimpleTreat 3.1. RIVM is currently revising SimpleTreat 3.1 for simulating municipal wastewater treatm...
Environmental Sciences Manager Malyka Galay Burgos
Administrative Assistant Sonia Pulinckx
The findings of the task force were published in October 2011 as ECETOC Technical Report No.112; "Refined...
Why?
The current paradigm for identifying data (study) requirements is based upon a surrogate of exposure, namely production volume, which may under or overestimate real exposure. As presented in ...
Why?
“Smart” or extended studies can be defined as in vivo studies that employ additional or different endpoints from conventional studies.They fall into 2 categories:those that follo...
Background
There has been a propensity by regulators to rely primarily on health surveillance/clinical case study data (case reports, clinical databases, worker exposure studies) to classify substa...
Background
Recent opinions published by the RAC on low top dose selection in animal toxicity studies have indicated an apparent intent of increasing dosages systematically in view of the criteria u...
